| Darsteller | Rolle |
|---|---|
| John Lithgow | John Mason (13) |
| Jeffrey Tambor | Jeffrey Pyne (13) |
| Jake Sandvig | Hugh Pyne (7) Hugh (13) |
| Heather Burns | Stella (13) |
| Ed O'Neill | Brock Manley |
| Tim Russ | Marty (3) |
| Judith Light | Gina (3) |
| Paula Cale | Annette (3) |
| Cynthia Sophiea | Dr. Jennifer Thompson |
| Gregory Jbara | Gary |
| Marcia Strassman | Mackenzie |
| James Black | George |
| James Hong | Dr. Fong |
| Brian Wade | Drew |
| Kareem J. Grimes | |
| Danielle Bisutti | Courtney |
| Heidi Dippold | Pamela |
| Kevin Chamberlin | Bailiff |
| Connie Ray | Susan |
| Joe Regalbuto | Richard |
| JoBeth Williams | Kate |
| Stephen Hibbert | |
| Christopher David | Young Jeffrey Pyne |
| Spencer Daniels | Young John Mason |
| Amy Aquino | Lois |
| Tiz McWilliams | Bartender |
| Paul Rogan | French Waiter |
| Stella Stevens | Martha |
| Rance Howard | Henry |
| Hunter Allan | Robbie |
| Steven Eckholdt | Doug McDowell |
| Gayle Samuels | Waitress |
| Marianne Muellerleile | Sonia |
| Sky McDougall | Magellan Adventurer |
| Mari Haig | Helen Grossman |
| Matt Price | Meriwether P. Lewis |
| Michael Worth | Frank |
| Kelly Crean | Maid |
| Ralph Cole Jr. | Barry |
| Sahar Bibiyan | R.N. |
| John Fleck | Barry |
| Kelley Daugherty | Lady at Funeral |
| Joe Duffy | |
| Jeremy Roberts | The Imposing Man |
| Katy Selverstone | Kristin |
| Robin Riker | Helen |
| Rod Keller | Laslow |
| Jane Leeves | Mary Frances |
| Nora Paradiso | Catherine |
| Mike Pachelli | Lawyer |